Originally Posted by
jags86
I thought I’d bump this as I believe the best “universal” hotel card is the Bank of America Business Advantage Customized Cash Card with Business Platinum Honors — you will earn 5.25% cashback on up to $50,000/yr in the travel category..
And that's generally nowhere near the value you can get from the hotel cobrands, suggesting that the answer to the question in the original post is "no".