I use to be able to do Rockville to Mars in 3.5 hours on Thanksgiving morning when I lived in Rockville.
if you do decide to drive, think long and hard about the option of the one way rental and the one way flight back mentioned upstring. The four years I did that drive for thanksgiving, the return on Sunday or Saturday was north of six hours with traffic. The final year, I did early Monday and it was easy peasy.