As good as any place to ask, mod please move if needed.

Two adults and 2 children, almost 4 and 8 in J on a 333, Layout 1 (4 abreast).

it was a bit challenging to select seats, as an adult needs to be adjacent to a child. First go I did all on 1 row, 5 ADGK. Figured the littlest one and one of the adults can be in D&G and with the partition slid open we can assist and keep.an eye on her. How realistic is that actually, can one actually reach over?

Then I wanted to maximize window placement so I played around and the system let me select 6G and 5K, 6K and 7K across the isle. With the seats at an angle to provide as much privacy as possible, would that make tending to a small child difficult?

Any other considerations, especially from the perspective of fellow passengers and flight crew?