Like in all of these threads, it all depends on what you value. But if you can afford it relatively easily (I assume that the cost is not completely trivial, like you inherited a billion dollars, or else you wouldn't be asking), I would suggest splurging on a few trips, like Emirates A380, Singapore and other Asian airlines, but fly them en route to a first-class vacation not just a flight for the sake of it. The fun is still there (or al least it will be when the COVID restrictions end).