Thanks guys for the info!

With my 4 legs allowed in SA, I was hoping for:
Santiago - Lima
Lima - Buenos Aires
Buenos Aires - Rio De Janeiro
Rio - Caracas.

It looks like they are all possible except for Caracas. Every flight I check goes through the states before hitting Caracas. Are there any flights from any of the above mentioned cities to Caracas?

The closest I can find for SA - North Africa is from Buenos Aires or Rio to MAD or London, then transfer down to Cairo or Casablanca/Tangier. Are there any direct flights from SA - Cairo, Tangier or Casablanca?