Hi. I have flights booked in 25/7. Flight was departing at 2055 hours. This suited me as work for NHS and am on a rota to work till 12 noon.

Ryanair have changed the flight time to 1600 hours which I can’t make. Traveling for a family wedding the next day

what are my rights here? Ryanair say no refund

Do I have a leg to stand on here with them ?

anything under EU261?

thanks