Cruise ships from Seattle travel the Pacific all the time, for timeliness if nothing else. That was the standard routing pre-COVID, with the stop at Victoria to fulfil PVSA requirements. Inside Passage will also add to pilotage costs (must run close to or more than $100k for that length of transit), and very likely speed reduction (in addition to timing the tide at Campbell River). The wide-open ocean is used as the ships can go at full speed.