Define "profit". If an airline made $12,000 per flight in bottom line financial statement profit, American would make somewhere around $30 Billion in profit per year. They don't.

The "cost" you provide above says it includes "flight crew wages, airport fees, maintenance and fuel". It costs a lot more to run an airline than these three items. Like airplanes at up to $300 Million each, 100,000 non-flight crew employees, etc., etc.