I was stranded in Arizona for two months and people suggested I drive home to NY. I decided that all the stops for food/toilet along with hotels, etc. would be more concerning that flyiing. Cleaning the seat area, wearing a mask and using hand sanitizer for the day is much easier than having to clean every single area I would need to use on a cross country drive.

I flew Southwest, middle seats were kept free, along with the first few rows and last few rows of the plane. I felt safe, but so strange being home and having to wear a mask and clean everything I touch for 14 days....

Good luck with whatever you decide!