I like a couple/three drinks on long-haul premium leisure travel. If I get it wrong, I also feel REALLY rough
I try to stick to the same type of drink - normally champagne (for some reason I am ok on champagne - wine make me headachey, champagne doesn't...). On have a few and, like others, drink LOADS of water.
So moderation, not mixing and lots of water tend to work out well.
Boo