Originally Posted by winkydink
I'm going to agree with Scott and say that your best bet is reinstalling. There was a recent article in the Wahington Post about a tech who spent 8+ hours cleaning up an infected machine and never quite got it right. Unless you've got oodles of free time on your hands, reinstall and get yourself a good Firewall and A/V software before you ever connect to the internet. On average, it takes less than 30 mins for an unpatched machine sitting on the Internet to get infected.
Last time I had a machine with over 400+ reported instances of spyware it took me 4 hours of non-stop work to clean. The machine was too important to reformat so the owner insisted I just clean it... Major task