On February 22, 2020, the Central Epidemic Command Center (CECC) stated that 110 confirmed cases of coronavirus disease 2019 (COVID-19) have been reported across 14 prefectures of Japan, and that more than 70% of the cases had contacted or suspected of contracting COVID-19 locally. Furthermore, the source of infection of multiple cases had not been identified, and cases linked to community and hospital clusters had also been reported. Japan has adjusted its original preventive measures to actions aiming at reducing harm to address the disease. On the other hand, the number of confirmed cases of COVID-19 is rapidly growing in South Korea with 346 cases reported so far. Over 70% of the cases had contacted or suspected of contracting the novel coronavirus locally. Of these cases, the source of infection of five cases had not been identified. Cases linked to clusters at a large church and a hospital have been reported recently in South Korea. Considering the frequent social exchanges and travel between Taiwan and the two countries, the CECC announced that the travel notice levels for South Korea have been raised to Level 2: Alert, the public is advised to practice enhanced precautions.