I would also make sure to visit the following thread on the ITA Matrix Powertools
ITA-Matrix-PowerTools - Userscript for Orbitz/DL/UA/AA/BA/CZ/IB/LA/LH/LX/TK
It has grown from a Chrome/Firefox/etc user script to a full fledged browser extension. It will take your ITA itinerary straight through to a number of airline booking site and many OTAs. Basically any site that support deep linking with full trip details (dates, flights, number of passengers, travel class).