This proposal is definitely workable, as long as you keep in mind a few considerations. A lot of people commute on a weekly or semi-regular basis. Obviously, you want your pay/compensation at the new job to make it worthwhile. The main expenses will be for lodging at your new job location and for travel to and from home. Other living expenses like food and entertainment shouldn't be any more than you would already spend at home.

Assuming you will need to travel on weekends, you should mostly know your schedule ahead of time. Unfortunately, there is no special place to go for low-cost advance purchase tickets. But you can keep your eye on prices and buy in advance when the price is right. If you choose the East Coast, it may be feasible to drive occasionally instead of flying. If you're on the West Coast, flying is your only option.. It all depends on where you live and work in relation to the airports. Another consideration the ability to spend your time off (weekends and vacation) at your new location. If you have a family to consider, they can possibly come to see you instead of you going home. And time zone differences can be overcome, because whatever you lose in one direction you make up in the other direction.

A flexible schedule will help make commuting easier. Also if the new job involves travel, you may be able to work that into your schedule. That would save you time and possibly money.