We drove both Pittsburgh to Myrtle Beach and Pittsburgh to Boston in the last several months - about 10 hours. I think that was about as far as I'd want to go.

I drive 7 hours several times a year to pick up MissCP at college, and did the round-trip in one day last year. The nearest airport is over an hour away from her, involves a connecting flight, and she'd have to pay fees for the luggage she brings home.