Originally Posted by
findark
My rule of thumb is never, ever book through a third party unless you have a very good reason to.
The huge difference (mostly relevant if you have status) is that you have to go through an intermediary to get any help with your reservation.
Yup. Nothing like, "Sorry, we can't help you with your reservation. You need to reach out to xxx."
For me, I can't think of many good reasons to book direct vs. OTA. Have I booked with OTAs in the past? Yes, but mostly on obscure non-US carriers where I am skeptical about their site.
Also, from a credit card points stand point, I am certain I will earn 5% for every dollar by booking direct.