I knows A321XLR can fly nonstop flight from O'Hare to Basel, Geneva, Helsinki, Stockholm, Pisa, Vienna.
According of Great Circle Mapper:
Great Circle Mapper
They sure can fly nonstop flight from O'Hare hub instead of EWR or IAD.
All I want to fly nonstop flight ORD to Basel, Switzerland. It will be very easy for me. I don't have stop in London-Heathrow anymore.