I'm intrigued by this post. I don't find any modes of traveling (except lengthy bicycling and walking) tiring except for (1) train or bus rides where I'm lurching a lot and have to hold on, (2) rides on a crowded subway where I have to keep moving around to accommodate the flow of passengers, and (3) long drives where I'm at the wheel and traffic is intense.
There is travel that I find stressful (the rush for unassigned seats, late trains, all taxi rides), but I don't think that's the same thing.
Seth