I believe that you would have no problem getting the ticket accepted at check-in for LGW-VCE. No reissue necessary.

But whenever I am getting tickets issued and there is any possibility of an airport change I ask for them to be issued to the city code (LON, CHI, NYC, etc.) which certainly makes it even less likely that there would be a problem. EMECO in CAI and CX at HKG certainly have no problem issuing like that.