I have also used Bangkok as my "center" in SE Asia and wind up with many entry stamps in a short time period. This includes several entries when my Thailand stay consisted of taking the free bus to/from DMK to BKK. Multiple Thai visas has never been a problem in Thailand,

but...

The multiple visas from Thailand was once a problem for me entering Canada. I was driving from Buffalo to Toronto. The agent at the bridge asked why there were so many visas from Thailand, was not happy with my explanation and had me pull over for extra scrutiny. The second agent frisked me, checked my rental car carefully, quizzed me and unpacked my suitcases. It was only when I pulled up my plane confirmation leaving Toronto in two days that he finally let me into the country. It took over an hour.