I’d wondered if it’s happened already. I know SQ have a business class only A350 running non stop between SIN and JFK (I hope it’s the right NYC airport and airport code for SQ’s hub) and I think more airlines are following this model for some flights.

On a slight side note, are LOT’s E70 and E75 approved for landing at LCY? Looking at the FR24 departure screen for LCY, most aircraft operating out of there are Embraer jets either 170, 175 or 190. Only Swiss are using A220’s and there are a couple of Dash 8’s and Saab’s operating but they are the minority.