The Greyhound out of FLL can be a pain. A one way car rental is usually about the same cost as the shuttle ($80ish) and is the way to go. Just be aware of tolls. You'll be fine without a car, it's only 2x4 miles. Uber's and Taxi's are pretty pricey here though. Depending on where you stay, some hotels have shuttles to old town and the city runs a free hop on loop bus once there. Plus walking or renting a bicycle.