We are going to be there for only 2 days, first time visit. This is next week with wife and 2 kids, so probably a little different focus than what you'd have. Also early for whale watching out of Vancouver (would have to go to Victoria Island this early) and we'll see how the weather is for biking.

Anyway, the things I researched include whale watching, the UBC area, Granville Island Public Market, biking around Stanley Park, Capilano Suspension Bridge, and maybe visiting Whytecliff Park on the way back from Whistler-Blackcomb. May give you some ideas.