Most of my flights are leisure these days (although myself and a collegue did once drink a full bottle of Aberfeldy in the Virgin Upper Class bar on a daytime flight from LHR to LAX).
If we're in a lounge with decent champers then I'll start with a couple of those, otherwise it would be a Vodka and Orange.
Once on board, more champers for the pre-departure drink, then a G&T once in the air.
If there's a bit of time before meal service then I'll have a second G&T.
White wine with the starters, red with the mains, port with the cheese (in F)
Finished off with a single malt as a digestive, then try and sleep it off for the rest of the flight.