Originally Posted by
kop84
yes skipping the first leg (or any leg) will cancel any remaining segments.
With the caveat that in certain IROP situations DL can set it up that it will allow you to use the return if you didn't fly the Outbound.
One can only hope for a weather waiver, delays, cancellations (very unlikely with DL), or a significant schedule change to avoid the $200 change fee. In addition, a change of operating carrier to/from mainline versus DL Connection flights or even from one DL Connection carrier to another (according to DOT regulations but I've had DL agents deny that this is the rule), but this would be very unlikely to apply to this route.