Thanks, all. This is tremendously helpful. The diversity of responses reinforces that it will be a gut call depending on the circumstances of a given itinerary.
My wife has a PSC-SEA-LHR round trip (AS/BA) when we arrive, and that will give us our first glimpse of what this will be like for us. Given her second leg is TATL, we chose PSC for that one, since it would be easier to rebook onto DL or UA if things go haywire. So we'll get the PSC drive in the winter experience just a couple days after we move in... joy.
I've already experienced the LONG connections at SEA - we decided to go on DL to PSC rather than AS to ALW during the interview because we'd have close to twelve hours if we flew from JFK. (Being on Long Island now, Newark wasn't an option.) As much as I love hanging in a Centurion Lounge, I don't love it THAT much...