For whatever reason I have a very hard time sleeping on airplanes, even lie flat seats don't help much. I'm envious of those that can (including my wife and kids). I've tried everything, but I've accepted that I'm simply going to feel like crap upon landing after some flights. I do ok on westbound flights to Hawaii, but Australia is hard on me. Eastbound red eyes from Hawaii are killer for me, but only on longer trips. I had family and clients in Hawaii and could often pull off flying in early afternoon, and depart very late in the evening back to DEN and do just fine, but if I spend more that a couple of days in Hawaii I'm pretty much screwed when I return, and I now simply budget a day to recover in my plans. That said, I didn't seem to have a problem flying ORD-MUC-FCO last year in a lie flat for the long portion, but once again my wife and kids did better than me.

Good thread, as I'm curious of anything I possibly haven't tried to make my travels a little easier.