I'm glad this thread has surfaced as I was just searching for it.
​​​​​​
I'll be on HND-LHR in First next year, as a pair, which is an all-day flight, in essence.

The cabin is totally open and I'm trying to decide whether there are any distinct or nuanced benefits to selecting a particular middle pair of seats.

Detailed advice appreciated. We're trying to sit away from the assigned baby bassinet seat in the instance of, well, a might-be-better-behaved-than-adults-but-might-not-be bambino.

Cheers