It isn't even necessarily a deposit. It's simply a hold on the funds required for the stay plus some property-specific daily amount for incidentals. It assures that your CL will cover your bill.
So long as you have a decent CL, this is insignificant. If you are going to travel on a low CL card, makes sure that you call your card issue in advance and ask to make certain that they will grant a temporary increase to cover the hotel.