Congratulations to the future Mrs DelrayChris and to you! ^
I believe there are several options, but it is a bit sad that you will not have 180k miles. If you did, you could take 2 (each 90k) SkyTeam Business class awards and do that whole thing for free. I think you'd use andy ST airline to FCO and then Alitalia to ATH and then any ST airline on the way back.
Now if you want to pay for a ticket and upgrade, be aware that upgrades on ST members is IMHO one of the weakest points of ST. Basically, forget it! The only thing you can upgrade are DL coded flight and operated by DL or AF and in the latter case, not beyond CDG. So you probably want to take the direct DL flight to Rome, then use AZ in Y and then back on the direct DL flight from ATH. Book early. This will set you back by 50k miles. Of course you can use one award and one upgrade, as to make things a bit more complex for the reservation agent. But they are great people
