My biggest concern with this idea is that the direct access window seats would be labelled "disabled friendly" when they're not - they might be for some but the major benefit they offer is that you don't have to climb over a footrest.
You still have to duck and twist and you can imagine the headlines and/or posts on here when a 6'6", 25-stone, 70-year-old who uses a cane/wheelchair tries to pour himself through the gap between the seat and the bulkhead.
I appreciate that there are people with sensory issues, etc. who might be able to benefit from those seats but they would be much worse than an aisle seat for many, as well.