I usually skip chain hotels.

Chain hotels often cost as much if not more than local boutique hotels and chain hotels often all look the same.
Boutique hotels often have interesting decor and such, not found in chain hotels which have to somewhat maintain a "common" design theme.

Staying all the time at a Hyatt or Hilton etc will get perks like nicer or free room, breakfast but those dont outweigh the positives that local boutique hotels provide.

I usually like the local breakfast when traveling which we dont get when eating at a generic hotel breakfast.