Don't forget that in bad weather, there can be traffic delays, significant ones, even if the planes are taking off without huge delays.

Make sure that you arrange extra time to get to the airport.
If there's, say, an accident on a highway en route, and traffic is at a standstill, you might risk missing your flight.
At the least, double check cancellation/change fees/rules for you ticket just in case, and make sure you call IF you are going to miss the flight.

As someone already mentioned, often in bad weather, it's more a problem of flights arriving than departing. But... a flight can't take off, if the plane wasn't able to land...

Try to monitor the flight schedule prior to arriving, and sign up for notifications if they are offered.

Quite some weather in Boston these days!

GC