This is a really broad question. The US is quite large with many different climate zones that will vary by season.
What are you looking for?
When are you looking to visit?
How much time do you have?
Single location or multiple spots?
I live in NY and am headed to Yosemite in California with my brother & father next week for some camping, meteorite watching (it's really dark there) and fly fishing which is something my family enjoys doing at our cabin in upstate NY. Excited for it but it's the kind of thing we really enjoy.