I just got a Bolt Backback by SF bags / Waterfield designs.
https://www.sfbags.com/products/bolt-backpack
Love it.
The quality is that of high end bags and they're made in SFO. You can customise the leather trim and the over all colour too. I went for ballistic nylon with chocolate leather.
There's two padded pouches for laptop and iPad. Side pockets for a water bottle. A hidden front pocket for a few bits and pieces that need to be secure and then the main compartment is large enough for your cables etc...