I live near LAX and work in Anaheim
I have tried every route possible for the past 9 year that I have been making this commute. The radio is a great idea personally am 640 (talk radio) is what I listen too but....rarely do I every change my course.
Take 105 East to 110 South to 91 East to 5 South.
There are lots of other ways to go but I have found less traffic problems this way.
Fridays are not good any way after 3:00pm and the difference between 2:45 and 3:00 can make a huge diffence.