Some recent experiences all from within the last couple of years - many airports have multiple visits but are only listed once.

JFK: No questions asked

MIA: No questions asked (though once questioned by customs due to a 1 night turn in LIM - mileage run - and was sent for extra baggage screening)

ORD: No questions asked

DFW: No questions asked

ATL: Got an X on my GE slip after indicating I had been on a farm on my trip (wedding in UK was in the countryside in a farm that still had live animals in a different section). Only had one agent working the GE "see agent" line so took nearly 25 minutes to get through. Thankfully bags took even longer so wouldn't have been any fast without the X. Those who did not get an X simply had to hold up the slip for the various CBP officers who were checking Crew slips and were waved through.

Oddly never been through CPB at RDU despite being my home airport since I always connect elsewhere before the final leg down to RDU.