Mrs. Stiff and I are flying YYZ-AMS in July and are in 1A and 3A. Not sure I'll even ask the passenger in 2A for a switch. We'll be 12 days joined at the hip once we get there so a few hours apart won't hurt.
OK, so my real answer is go for the A's or K's. You'll be busy with movies and books and such anyhow, and that way you both get windows for the daylight portion of the flight.