You'd want to find a way to LAX that reliably avoids the Sepulveda exit from the 105-- it's been very inconsistent lately and there have been a few times where the mile or so from the line to exit there to T1 was the longest part of my trip to LAX, and I'm coming from just north of Pasadena.

Transcon commuting can get old- for a couple years I was going LAX-IAD about once a month (generally 2-3 days on the ground, sometimes a week). A few times I had to do the RT with only a few days on the ground back at home, and those weren't a lot of fun. It was made worse by my day job usually being a commute Pasadena to Manhattan Beach (which is a horrible commute) and a lot of the trips to IAD on short notice over weekends. Another former poster here was commuting every week transcon across Canada, and it showed...it was clearly pretty hard on him, even when he didn't think so.