Piece of cake! Can of corn! ...are there any more of those?
PTY is a brilliant hub for making connections, you'll probably have to walk a little bit to get to the gate, and yes there's extra screening for a US flight. CM also seems to board ridiculously early, so don't be surprised if you get there for last call.
But this shouldn't be an issue at all.
Makes me wish I was transferring at PTY tomorrow and not MEX where a 3 hour INTL cnx can be tight.