For these types of general questions about a specific area, it's often the forum members that know most about this type of question rather than TA's, especially if you are limiting the hotel choice to Virtuoso since most of the lodges won't be affiliated with that consortium. Really not the logical way to start. It's better to learn an area first, before looking at a limited group of hotel choices.

I think the OP is taking the most logical first step in this case, and am glad that this board is now open luxury travel rather than just "hotel rooms in major chains" as it was in the past, where this type of question would have been sent to a destination forum earlier. (not wise since luxury travel does not equal luxury hotel chain rooms.)

There's a new Awasi being built in Iguassu falls and the Pantanal might be a really interesting place to visit. We ourselves are going to Sacha lodge in Ecuador next month, which is a jungle/amazon lodge and certainly a luxury option considering where it's at in my opinion, and it sounds similar to what you might enjoy.