Let me give the slight case for 1A and 1C on the G-GAT series, not that I would normally want to select there. On a less than full aircraft, on say a trip under 2 hours, the CE cabin will be operated by the SCCM, and won't be in that space very much. During take off and landing, if there is only one passenger in (say) 1A, the second crew member may sit in 1C during take off and landing. Queues for the WC may well not happen on a shorter sector, and so you would have for pretty much all the flight have unlimited leg room and reasonable privacy. I think you would need to be over 2 metres tall for this to make much difference, but that row is not a total disaster for all passengers all of the time. I know some passengers select that row deliberately and are happy with it.