Last year, I did 2 x 24hr connections in Egypt. I really have no negative experiences.

Yes there are touts (everywhere - airport, pyramids, museum, CBD), but it must be remembered that they are only trying to carve out a living in a very low socioeconomic environment. On the other hand, if you are silly enough to pay over the odds, fall for a simple trick, they will show no mercy and grab any offered money with both hands.

On our first connection, we did stay at a Pyramid hotel, with stunning views of the Pyramids from our bedroom window. We caught a taxi from the airport to the hotel. That afternoon we did a private Pyramid visit via horse and cart - spectacular. In the evening we watched (and listened) the Pyramid light show from our hotel rooftop, whilst enjoying dinner. Next morning we visited the Egypt Museum (booked a hotel driver) at opening time, luggage remained in the car with the driver who picked us up at the prearranged time and took us to the airport.

The other visit had us flying out of Alexandria.
We caught a taxi from the CAI airport to Cairo railway station. I had a prebooked rail internet ticket for the journey to Alex - very comfortable and scenic trip up the Nile. From Alex train station, a taxi to our hotel. Next day we were not flying out of HBE until 6pm, so I organized a private "highlights tour" (with luggage in the trunk) of Alexandria with the day ending at HBE airport.

I felt neither ripped off or threatened on both visits. Actually, we met some very nice Egyptians who went out off there way to help us (and they were not expecting or looking for a tip).

So here would be my advice :
Do your homework. Have some understanding of where infrastructure (airports, hotels, scenic sights) is located. Read current posts on here and TA - a lot of posters provide the cost of of services that they experienced. But, caution with this - their can be a element of blagging, and knocking the cost of services down to basement prices does not normally provide a quality service.
When you are touring, it's quite likely that you are far more wealthy that people you meet (including touts) in the service industry. In a dignified and unobtrusive manner try and spread a little joy, without making yourself look like a rich dumb target.

I never let a tout choose me (as a example, by ripping a bag out of me hand) - I choose the tout (ie service provider) and pay him/her a modest fee related to their quality of service.

We saw wonderful things in Egypt - recommended.