Benzodiazepines and opioid medications are DEA scheduled drugs, meaning that administration of such drugs must first be authorized by someone licensed by the DEA to do so, at least in the USA.

I assisted in the care of a patient who had an inflight anaphylactic reaction on a DCA-LAX flight in 2012. Before the FA would allow me access to the inflight medikit I had to show her my medical license as well as my DEA certificate, and she asked for quite a bit of personal information.