It's nontrivial, since KIX is (way) to the south of Osaka, while ITM is to the north. The most practical option is the direct "limousine" bus (80 minutes, ~Y2000, subject to traffic). Transportation buffs might want to consider taking Nankai to Umeda, Hankyu to Hotarugaike or Senrichuo, and then the Osaka Monorail to ITM, but this obviously requires two connections and Umeda in particular is not the easiest station in the world to navigate.