My hellish flight was from AMS to JFK.
It was a KLM flight, in a 747 that was half passenger and half cargo - they did make those back in the day.
On our flight, the cargo was racehorses. Half way across the Atlantic, their sedation wore off and they started thrashing around and kicking. You could hear them clearly and their banging around rocked the plane quite severely.
Airline staff kept rushing to the back of the plane and through a door, presumably to try to help, or to instruct the handlers to get things under better control.
The banging and rocking continued for the rest of the flight - it was worse than some turbulence I've encountered.
It was a great relief to land safely at JFK.
I understand that nowadays racehorses are only carried on flights that are purely freight, not passenger flights.