Good call that you really have to break this down into regions of KC, Carolina, Texas, etc ...
But since I'm in Texas at the moment, I'll consider that ... Goode Company Barbecue in Houston, hands down. You're not going to find a better brisket. And the only place you'll find better ribs are, well, in my back yard.
Of course, I can't say that County Line and the Salt Lick in Austin are bad, though ...
As we're quickly finding out, when it comes to barbecue, you just can't go wrong with it when it's really, really good. I'm starting to get hungry.