While many have suggested using IB for flights to South America, I take a slightly convoluted routing and fly AA either through DFW or MIA.
MIA offer an F cabin to certain destinations, while DFW offers the 787-8 and 787-9s, with the latest AA J product.
The crews on the flights to South America, tend to be locals from that country, so they're full of helpful knowedge.
I fly with them opposed to IB, because MAD is a hassle to position into (from LHR on BA).
M