No matter what the line, repositioning cruises - esp TATL - seem to have some of the lowest per diems of any options offered by that line. I've definitely been eyeing them over the years. Haven't bitten yet - not enough time in the year to do all I want -but would love to get on a luxury line at a premium line price.
Husband shares the same concern about how enjoyable that many sea days on a small Seabourn ship in the Atlantic might be

(and I'm the one who gets seasick! But I have drugs for that

)
Have also considered doing a TATL crossing instead of flying back after a vacation (we're on the east coast of the US which makes it somewhat easier to consider). Have (retired) friends who do that regularly - hey, a crossing on the Queen Mary 2 is cheaper than business class seats. Could be even cheaper than coach, depending on specifics, so....