I have both a Mei Voyageur and a Osprey Farpoint 40. The Mei I have is a bit too large around the hip to the point that the tightest setting does not wrap my hips. I wasn't asked for my hip size, so make sure you get them to make it smaller or customise it to your needs if you don't want extra straps dangling off your hip. Maybe it is because I've abused it too much since 2010, but I find the backpack to carry a little oddly these days, with the metal bars that act as support at the back protuding a little too much, which makes the back a little uncomfortable when carrying.
I'm quite impressed with the Osprey so far, but it's very new and I've not had the chance to test it on the roads yet. It doesn't look as business-like though.